Mini2P Headbars

Founding developers Edvard Moser, May-Britt Moser, and Weijian Zong

 
Accessories for Mini2P Headbars

Founding developers Edvard Moser, May-Britt Moser, and Weijian Zong

Edvard Moser and May-Britt Moser lead the Kavli Institute for Systems Neuroscience in Trondheim, Norway. In 2014 they received the Nobel Prize in Physiology or Medicine.

Weijian Zong is a researcher at the Kavli Institute for Systems neuroscience where his main research interests are bio-imaging, neuroscience, neuronal computation.


The Mini2P is a 2-photon miniscope for large-scale calcium imaging in freely moving mice. It enables stable simultaneous recordings of over a thousand cells across multiple planes of densely active cortical regions during a wide range of behavioral tasks without affecting the animal's behavior.

EXPERIMENTAL CAPABILITIES

The experimental setup involves attaching a titanium 'Mini2P Headbar' to the skull and cannula. The combination of cannula, headbar, and skull forms a stable and rigid frame for positioning any implanted optics. 
There are currently 3 variants of headbars being offered:
  1. M2P Headbar-0d
      • Use for posterior cortex
      • Use for CA1 Imaging (medial part)
      • Use for neocortex Imaging (posterior-medial part)
  2. M2P Headbar-20d
      • Use for lateral cortex
      • Use for MEC Imaging
      • Use for CA1 imaging (lateral part)
      • Use for neocortex imaging (posterior-lateral part)
  3. M2P Headbar-0L
      • Use for frontal cortex
      • Use for neocortex imaging (anterior part)

KEY FEATURES

  • Made of titanium 

    CONTENTS 

    • Mini2P headbars

    PUBLICATION

    W Zong, HA Obenhaus, ER Skytøen, H Eneqvist, NL de Jong, R Vale, MR Jorge, MB Moser, EI Moser (2022). Large-scale two-photon calcium imaging in freely moving mice. Cell.

    Documentation Source Code Forum


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