Mini2P - Scope

Founding developers Edvard Moser, May-Britt Moser, and Weijian Zong

Accessories for Mini2P - Scope

Founding developers Edvard Moser, May-Britt Moser, and Weijian Zong

Edvard Moser and May-Britt Moser lead the Kavli Institute for Systems Neuroscience in Trondheim, Norway. In 2014 they received the Nobel Prize in Physiology or Medicine.

Weijian Zong is a researcher at the Kavli Institute for Systems neuroscience where his main research interests are bio-imaging, neuroscience, neuronal computation.


The Mini2P is a 2-photon miniscope for large-scale calcium imaging in freely moving mice. It enables stable simultaneous recordings of over a thousand cells across multiple planes of densely active cortical regions during a wide range of behavioral tasks without affecting the animal's behavior.

EXPERIMENTAL CAPABILITIES

The Mini2P Scope accepts the excitation fiber for delivering the 2-photon laser, and the resulting fluorescence is directed into the Mini2P- Collection Fiber v1. The two versions of the Mini2P-Scope have either a fast or a wide-angle MEMS mirror. Also, three different objectives are available. The Mini2P- Scope Cable Harness v1 provides to the Mini2P Scope the driving signals for the µTlens and the MEMS mirror. The supplied baseplate and the intermittent stitching adaptor (0,0) forms the connection to the mice.

The Mini2P Scope is fully tested and individually characterized. We measure and provide resolution, viewing angle, and z-stack straightness of each instrument. These values allow you to optimize scope performance to its fullest potential.

KEY FEATURES

  • Weight: 2.2g
  • Fast response time: 1.5ms
  • Wide Angle FOV: 0.5x0.5mm² or Fast MEMS scale FOV: 0.42x0.42 mm²
  • Different objectives allow different media
  • Large Z-scan range: 240µm

CONTENTS 

  • Mini2P Scope with individual specification sheet
  • Choice of MEMS mirror: fast or wide-angle
  • Choice of objective: three types
  • 1x Stitching adaptor
  • 1x Base plate

PUBLICATION

W Zong, HA Obenhaus, ER Skytøen, H Eneqvist, NL de Jong, R Vale, MR Jorge, MB Moser, EI Moser (2022). Large-scale two-photon calcium imaging in freely moving mice. Cell.

Documentation Source Code Forum


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