Mini2P Implant (Pack of 5)

Founding developers Edvard Moser, May-Britt Moser, and Weijian Zong

 
Accessories for Mini2P Implant (Pack of 5)

Founding developers Edvard Moser, May-Britt Moser, and Weijian Zong

Edvard Moser and May-Britt Moser lead the Kavli Institute for Systems Neuroscience in Trondheim, Norway. In 2014 they received the Nobel Prize in Physiology or Medicine.

Weijian Zong is a researcher at the Kavli Institute for Systems neuroscience where his main research interests are bio-imaging, neuroscience, neuronal computation.


Note: The units are currently in production. If immediate shipment is required, we can dispatch the set of components included in each variant without gluing.

The Mini2P is a 2-photon miniscope for large-scale calcium imaging in freely moving mice. It enables stable simultaneous recordings of over a thousand cells across multiple planes of densely active cortical regions during a wide range of behavioral tasks without affecting the animal's behavior.

EXPERIMENTAL CAPABILITIES

The experimental setup involves attaching a custom-made titanium head-bar to the skull and cannula. This combination of the cannula, head-bar, and skull forms a stable and rigid frame for positioning the scope.

Contact LABmaker for different assemblies, e.g. involving a GRIN lens or longer prism.

 The different variants of Mini2P implants currently offered are:

1. Prism 1.6x1.3 Assembly

  • Implant for MEC, RSC, PFC, and vertical view of neocortex
  • Compatible with D0277 Objective Lens

2. Plug 1.8x1.5 Assembly with Cannula

  • Implant for CA1 imaging
  • Compatible with D0277 Objective Lens

3. Plug 1.8x1.5 Assembly w/o Cannula

  • Implant for neocortex imaging
  • Compatible with D0277 Objective Lens

4. Coverslip 5x0.15 Assembly

  • Implant for neocortex imaging
  • Compatible with D0254 Objective Lens

5. Coverglass 4.6x1.9 Assembly

  • Implant for neocortex imaging
  • Compatible with D0277 Objective Lens

KEY FEATURES

1. Prism 1.6x1.3 Assembly

  • Prism 1.6x1.3 + Coverslip 5x0.15 + Cannula 5.1x2
  • Glass + AR coating
  • FOV change range: 1.3 mm

2. Plug 1.8x1.5 Assembly with Cannula

  • Plug 1.8x1.5 + Coverslip 5x0.15 + Cannula 5.1x2
  • Glass + AR coating
  • FOV change range: 1.5 mm

3. Plug 1.8x1.5 Assembly w/o Cannula

  • Plug 1.8x1.5 + Coverslip 5x0.15
  • Glass + AR coating
  • FOV change range: 1.5 mm

4. Coverglass 5x0.15 Assembly

  • Coverglass 4.6x1.9 + Coverslip 5x0.15 + Cannula 5.1x2
  • Glass + AR coating
  • FOV change range: 4 mm

5. Coverslip 4.6x1.9 Assembly

  • Coverslip 5x0.15 + Cannula 5.1x2
  • AR coating
  • Larger field of view
  • FOV change range: 5mm 

PUBLICATION

W Zong, HA Obenhaus, ER Skytøen, H Eneqvist, NL de Jong, R Vale, MR Jorge, MB Moser, EI Moser (2022). Large-scale two-photon calcium imaging in freely moving mice. Cell.

Documentation Source Code Forum


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