Chi.Bio Reactor Only (7-color LED)

Founding developers Harrison Steel, Robert Habgood, Antonis Papachristodoulou


Accessories for Chi.Bio Reactor Only (7-color LED)

Founding developers Harrison Steel, Robert Habgood, Antonis Papachristodoulou

Chi.Bio was created by an engineering PhD Student, Harrison Steel, together with postdoctoral researcher Dr Robert Habgood and Professor Antonis Papachristodoulou at the University of Oxford. The platform was initially developed to assist the inventors with their own research in synthetic biology, and was then developed into an open-source project due to widespread demand for its capabilities.


For instructions on how to operate Chi.Bio, please see the Operation Manual

Chi.Bio is an all-in-one experimental automation device for characterisation and manipulation of biological systems. Its broad feature set allows researchers to perform and automate many common experimental protocols from synthetic, systems, and evolutionary biology, without requiring any additional laboratory hardware. It can operate as a Turbidosotat or Chemostat to regulate cell growth, whilst providing heating, stirring, measurement of multiple fluorescence proteins, and optogenetic/UV/daylight inputs.

By combining regulation of biological parameters of interest and accurate measurement into a single platform Chi.Bio facilitates reliable and repeatable experimental procedures, which have long been recognised as a major challenge for biological science research.

Up to eight Chi.Bio reactor units can interface with each control computer, which runs the platform’s open-source operating system (developed in Python). A web interface (accessible on a connected PC or network) plots data in real-time as it is collected, and allows users to change and control ongoing experiments.

We are offering a very limited last batch of Chi.Bio Reactors with the 7-Color LED, specifically for users who need this functionality for their experiments. This is due to end-of-life for the 7-color LED.


  • Culture temperature regulation from ambient temperature to 55 °C
  • Measurement of multiple orthogonal fluorescent protein concentrations in situ (including RFP), actuation of optogenetic systems
  • UV LED (to encourage mutation) and 6500K daylight LED (for photosynthetic systems)
  • Growth regulation (turbidostat functionality) via measurement of culture optical density and input of fresh/removal of waste media
  • In silico control of biological systems by integration of multiple inputs/outputs


  • Six LED outputs of varying wavelength across the visible range, as well as 6500k daylight LED, 285nm UV LED
  • Optical output power-regulated laser diode
  • Spectrometer with nine measurement bands across the visible range, and integrated temperature calibration, adjustable gain, integration time, and aperture
  • Medical-grade Infrared Thermometer for measurement of culture temperature, and heat plate


  • Reactor with 7-Colored LED (incl. x1 glass vial and  x1 magnetic stir bar)

Note: Our regular Chi.Bio set now includes the 'Reactor with 5-Colored LED', due to discontinuation of the 7-Color LED component. If you do not specifically require the 7-Color LED Chi.Bio Reactors for your research, you can click here to make purchase and know more about the new version of Chi.Bio set. 


• Harrison Steel, Robert Habgood, Ciarán Kelly, Antonis Papachristodoulou. Chi.Bio: An open-source automated experimental platform for biological science research. BioRxiv.

• Harrison Steel, Robert Habgood, Ciarán Kelly, Antonis Papachristodoulou. In situ characterisation and manipulation of biological systems with Chi.Bio. PLoS Biol 18(7)

For any further enquiries related to this product, please contact us.

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