Founding developer Mathew Rynes, Leila Ghanbari, Micheal Laroque, Greg Johnson, Daniel Sousa Schulman and Suhasa Kodandaramaiah
$3,990.00 USD $4,490.00 USD
The Craniobot is a cranial microsurgery platform that combines automated skull surface profiling with a computer numerical controlled (CNC) milling machine to perform a variety of cranial microsurgical procedures in mice. The Craniobot utilizes a low force contact sensor to profile the skull surface and uses this information to perform micrometer-scale precise milling operations within minutes. The procedure of removing the sub-millimeter thick mouse skull precisely without damaging the underlying brain can be technically challenging and often takes significant skill and practice. This can now be overcome using the Craniobot.
The z-axis probe is prone to damage but can easily be replaced.
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• Leila Ghanbari, Mathew L. Rynes, Jia Hu, Daniel S. Schulman, Gregory W. Johnson, Michael Laroque, Gabriella M. Shull & Suhasa B. Kodandaramaiah (2019). Craniobot: A computer numerical controlled robot for cranial microsurgeries. Scientific Reports.
• Rynes ML, Ghanbari L, Schulman DS, Linn S, Laroque M, Dominguez J, Navabi ZS, Sherman P & Kodandaramaiah SB (2020). Assembly and operation of an open-source, computer numerical controlled (CNC) robot for performing cranial microsurgical procedures. Nature Protocols.