Founding developer Mathew Rynes, Leila Ghanbari, Micheal Laroque, Greg Johnson, Daniel Sousa Schulman and Suhasa Kodandaramaiah
$3,990.00 USD $4,490.00 USD
The Craniobot is a cranial microsurgery platform that combines automated skull surface profiling with a computer numerical controlled (CNC) milling machine to perform a variety of cranial microsurgical procedures in mice. The Craniobot utilizes a low force contact sensor to profile the skull surface and uses this information to perform micrometer-scale precise milling operations within minutes. The procedure of removing the sub-millimeter thick mouse skull precisely without damaging the underlying brain can be technically challenging and often takes significant skill and practice. This can now be overcome using the Craniobot.
The Craniobot Courier is a custom Graphical User’s Interface that runs in a MATLAB environment. This software allows the user to probe complex topographies and generate tool-paths tailored to each surface. The z-axis probe measures and stores point by point and generates a point-cloud. This point-cloud is then used to calculate the milling tool-path based on the surface mapped.
The z-axis probe is prone to damage but can easily be replaced.
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• Leila Ghanbari, Mathew L. Rynes, Jia Hu, Daniel S. Schulman, Gregory W. Johnson, Michael Laroque, Gabriella M. Shull & Suhasa B. Kodandaramaiah (2019). Craniobot: A computer numerical controlled robot for cranial microsurgeries. Scientific Reports.
• Rynes ML, Ghanbari L, Schulman DS, Linn S, Laroque M, Dominguez J, Navabi ZS, Sherman P & Kodandaramaiah SB (2020). Assembly and operation of an open-source, computer numerical controlled (CNC) robot for performing cranial microsurgical procedures. Nature Protocols.